Thesis Pascale Creignou-Mercier

Pascale Creignou-Mercier

Epidemiological bases for the control of caprine paratuberculosis

Abstract :

This study aimed at providing descriptive epidemiological knowledge about the infection of goats by Mycobacterium avium subspecies paratuberculosis, in order to design control schemes. A serological study confirmed that Map infection was widespread in goat herds in France (true prevalence estimated to 63%). Detection of infected animals can be made by ELISA, with a sensitivity of 53% and a specificity of 100%. Best values for ELISA tests were obtained for goats aged 2-3 years. For detection of infectious animals, PCR was the earliest test (from 8 months of age). With PCR as reference test, sensitivities for IFNg test and ELISA test were estimated to 49 and 29%, respectively. Specificities for the 2 tests were estimated to 100%. Lastly, results are discussed in the perspective of the implementation of infection control schemes and further research topics are proposed.

Key words :

Goat, Mycobacterium avium subspecies paratuberculosis, test, epidemiology

Modification date : 11 September 2023 | Publication date : 29 June 2017 | Redactor : ML